• image.alt
  • With Mayo Clinic asthma and allergy specialist

    James T. Li, M.D.

    read biography

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Question

Alcohol allergy: Is there such a thing?

Is there such a thing as alcohol allergy? After drinking just one alcoholic beverage, I get a rash all over and I throw up.

Answer

from James T. Li, M.D.

Some people are more sensitive to the effects of alcohol than are others. However, this doesn't mean you have an alcohol allergy.

A true food allergy involves your immune system. In such cases, your immune system mistakenly identifies a specific food or a component of that food as a harmful substance. Your immune system triggers certain cells to produce immunoglobulin E (IgE) antibodies to fight the "enemy" food or food component. Signs and symptoms of food allergy include tingling in the mouth, hives, breathing difficulties, and swelling of your lips, tongue or throat.

An alcohol allergy would be very uncommon. However, you could be allergic to other ingredients in an alcoholic beverage, such as wheat or sulfur dioxide, a preservative. There are also substances in some alcohol beverages such as wine that can cause flushing or even rashes.

Still, it's more likely that you have an alcohol intolerance — which means you are more sensitive to the normal effects of alcohol. Alcohol can cause a variety of immediate adverse effects on the body, including headache, rapid heartbeat, nausea or vomiting, heartburn, abdominal pain, nasal congestion, or warm, red, itchy skin.

Many people of Asian descent experience an unusual flushing reaction after drinking alcohol — even in very small amounts. This is caused by a genetic disorder in which the body is unable to break down alcohol completely. Some research suggests that people who experience alcohol flush reaction may be at increased risk of alcohol-related conditions, such as cancer of the esophagus and liver disease.

The only solution to all of these problems is to avoid alcohol.

Rarely, severe pain following alcohol ingestion may be a sign of a more serious underlying disorder, such as Hodgkin's disease — also known as Hodgkin's lymphoma. If you experience unusual symptoms after ingesting alcohol, consult your doctor.

Next question
Food allergy: Can it develop later in life?

AN00818

March 12, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger